Xiaohui Xie
Xiaohui Xie
My research program focuses on advancing the foundations and applications of artificial intelligence, with an emphasis on machine learning methods that integrate statistical rigor, scalability, and real-world impact. A central theme of my work is developing next-generation learning algorithms—ranging from deep neural networks to large-scale generative and foundation models—that can reason, generalize, and operate reliably in complex environments. I am particularly interested in representation learning, efficient fine-tuning, memory-augmented architectures, and reinforcement-learning–based agents as steps toward more general and adaptive AI systems. I am also deeply interested in applications of these methods to biology and medicine, where AI can drive scientific discovery, enhance clinical decision-making, and improve population health.