The UCI Teen Resilience Lab conducts research on the modifiable pathways linking early experiences of stress and adversity to lifelong risk for depression and other chronic health conditions. Of particular interest are the ways in which experiences of stress during sensitive periods of development change the ways the brain and immune system communicate and how the body responds to subsequent stress. The vast majority of our research is conducted during adolescence when depression risk in the population experiences a dramatic rise that persists into early adulthood.